Welcome to MetaBridge v1.2, a user-friendly web tool for network-based integrative analysis of metabolomics data. Here you can upload a set of metabolites and identify the directly interacting enzymes for network integration.
To start, you'll want a set of metabolites as HMDB, KEGG, PubChem, or CAS IDs. We recommend MetaboAnalyst for metabolomics data processing, as well as ID conversion if you have only compound names.
With the output of MetaBridge, you can create a protein-protein interaction network representative of your metabolomics data. We recommend NetworkAnalyst for generation of these networks and for network-based integration with protein-protein interaction networks created from other omics types.
MetaBridge was developed at the Hancock Lab using data from MetaCyc (Version 23.0) and KEGG (Release 92).
Click the button below to Get Started! If you'd like to learn more about how MetaBridge can be used, check the Tutorial. For more information, refer to the About page.
To start using MetaBridge, you need to upload a list of compounds of interest as metabolite IDs. If you are starting with raw metabolomics data, you will need to preprocess your metabolites with your method of choice to obtain compounds of interest and their corresponding metabolite IDs. We recommend MetaboAnalyst for metabolite preprocessing.
Upload your metabolites to MetaBridge and select your metabolites for mapping.
Choose a database to map against and view your mapping results.